The function of ENSG00000175868 (CALCB, calcitonin related polypeptide beta) is as follows. CALCB/CGRP2 is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex (PubMed:1318039, PubMed:9620797). Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role (PubMed:3492492). {ECO:0000269|PubMed:1318039, ECO:0000269|PubMed:3492492, ECO:0000269|PubMed:9620797}.