The function of HES7 (hes family bHLH transcription factor 7, Ensembl gene identifier ENSG00000179111) is as follows. Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation (By similarity). .