The function of Ensembl gene identifier ENSG00000182919 (BKGD, beta-keto-L-gulonate decarboxylase) is as follows. Catalyzes the decarboxylation of 3-dehydro-L-gulonate to produce L-xylulose, used in the pentose pathway (PubMed:40737316). Exhibits ester hydrolase activity on p-nitrophenyl acetate, in vitro (PubMed:16522806). Regulates DNA damage and repair by regulating HIF1A degradation via chaperone-mediated autophagy (CMA) (PubMed:37277441). {ECO:0000269|PubMed:16522806, ECO:0000269|PubMed:37277441, ECO:0000269|PubMed:40737316}. [Isoform 3]: Probably non-functional when tested on p- nitrophenyl acetate, in vitro. .