Rho subunit of the pentameric ligand-gated chloride channels responsible for mediating the effects of gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain (By similarity). Rho-containing GABA-gated chloride channels are a subclass of GABA(A) receptors (GABAARs) entirely composed of rho subunits, where GABA molecules bind at the rho intersubunit interfaces (By similarity). When activated by GABA, rho-GABAARs selectively allow the flow of chloride anions across the cell membrane down their electrochemical gradient (By similarity). {ECO:0000250|UniProtKB:P24046, ECO:0000250|UniProtKB:P50573}. This is the function of Ensembl gene identifier ENSG00000183185 (GABRR3, gamma-aminobutyric acid type A receptor subunit rho3).