The function of Ensembl gene identifier ENSG00000184207 (PGP, phosphoglycolate phosphatase) is as follows. Phosphatase with activity against multiple substrates (PubMed:27294321). Acts as a metabolite repair enzyme which eliminates toxic glycolytic side products (PubMed:27294321). Dephosphorylates 2- phosphoglycolate which is generated during the repair of oxidative DNA lesions (PubMed:26755581, PubMed:27294321). This controls triosephosphate isomerase activity, glycerolipid partitioning and cell proliferation in the embryo and is required for embryonic development (By similarity). Dephosphorylates 4-phosphoerythronate, a side product which is produced by GAPDH and which inhibits 6-phosphogluconate dehydrogenase (PubMed:27294321). Dephosphorylation of 4- phosphoerythronate prevents the accumulation of high 4- phosphoerythronate levels which would otherwise inhibit the pentose phosphate pathway (PubMed:27294321). Dephosphorylates 2-phospho-L- lactate which is a product of a pyruvate kinase side reaction (PubMed:27294321). This prevents the inhibition of fructose-2,6- bisphosphate production and allows glycolysis to occur (PubMed:27294321). Has glycerol-3-phosphate phosphatase activity, hydrolyzing glycerol-3-phosphate into glycerol and thereby regulating the cellular levels of glycerol-3-phosphate, a metabolic intermediate of glucose, lipid and energy metabolism (PubMed:26755581). Has been shown to have tyrosine-protein phosphatase activity although the physiological relevance is unclear (PubMed:26755581). In vitro, has phosphatase activity toward ADP, ATP, GDP and GTP (By similarity). {ECO:0000250|UniProtKB:Q8CHP8, ECO:0000269|PubMed:26755581, ECO:0000269|PubMed:27294321}.