The function of NUDT17 (nudix hydrolase 17, Ensembl gene identifier ENSG00000186364) is as follows. Acts as a decapping enzyme capable of hydrolyzing monomethylated capped RNAs (in vitro). Hydrolyzes monomethylated capped RNA after alpha and beta phosphates to form N(7)-methyl-GDP. Shows low activity towards unmethylated capped RNA. .