The function of P2RX2 (purinergic receptor P2X 2, ENSG00000187848) is as follows. ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium (PubMed:10570044, PubMed:31636190). Activation by extracellular ATP induces a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis (By similarity). In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling (PubMed:23345450). Mediates synaptic transmission between neurons and from neurons to smooth muscle (By similarity). {ECO:0000250|UniProtKB:Q8K3P1, ECO:0000269|PubMed:10570044, ECO:0000269|PubMed:23345450, ECO:0000269|PubMed:31636190}.