The function of Ensembl gene identifier ENSG00000188641 (DPYD, dihydropyrimidine dehydrogenase) is as follows. Involved in pyrimidine base degradation (PubMed:1512248). Catalyzes the reduction of uracil and thymine (PubMed:1512248). Also involved the degradation of the chemotherapeutic drug 5-fluorouracil (PubMed:1512248). .