The function of ZNF512B (zinc finger protein 512B, ENSG00000196700) is as follows. Involved in transcriptional regulation by repressing gene expression (PubMed:39460621). Associates with the nucleosome remodeling and histone deacetylase (NuRD) complex, which promotes transcriptional repression by histone deacetylation and nucleosome remodeling (PubMed:39460621). Sequence-specific DNA-binding protein that recognizes repetitive and non-consecutive TTC sequences in pericentric repeat and initiate heterochromatin formation through interaction with SUV39H1/2 methyltransferases which catalyze histone H3K9 methylation (By similarity). {ECO:0000250|UniProtKB:Q6PHP4, ECO:0000269|PubMed:39460621}.