The function of S100A6 (S100 calcium binding protein A6, Ensembl gene identifier ENSG00000197956) is as follows. May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative. . (Microbial infection) Facilitates attachment and invasion of Toxoplasma gondii parasites. .