Component of the large ribosomal subunit (PubMed:25901680). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:25901680). Binds directly to 26S ribosomal RNA (PubMed:25901680). . This is the function of RPL12 (ribosomal protein L12, Ensembl gene identifier ENSG00000197958).