The function of SULT1C4 (sulfotransferase family 1C member 4, ENSG00000198075) is as follows. Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic compounds. Can also sulfonate estrogenic compounds, however, the dietary flavonoids (phytoestrogen) and environmental estrogens, like bisphenol A are better substrates than 17beta-estradiol (E2) (PubMed:17425406, PubMed:26948952, PubMed:28222028, PubMed:9852044). Mediates the sulfation of doxorubicin and its analog epirubicin, two antitumor anthracyclines (PubMed:26948952). {ECO:0000269|PubMed:17425406, ECO:0000269|PubMed:26948952, ECO:0000269|PubMed:28222028, ECO:0000269|PubMed:9852044}.