Positive regulator of amyloid protein aggregation and proteotoxicity (PubMed:20723760, PubMed:22854022, PubMed:31034892). Induces conformational changes in amyloid proteins, such as APP, HTT, and SNCA, driving them into compact formations preceding the formation of aggregates (PubMed:20723760, PubMed:22854022, PubMed:31034892). {ECO:0000269|PubMed:20723760, ECO:0000269|PubMed:22854022, ECO:0000269|PubMed:31034892}. This is the function of SERF1B (small EDRK-rich factor 1B, Ensembl gene identifier ENSG00000205572).