Promotes CCP110 ubiquitination and proteasome-dependent degradation. By counteracting accumulation of CP110, maintains normal centriolar homeostasis and preventing formation of ectopic microtubular organizing centers. {ECO:0000269|PubMed:22261722, ECO:0000269|PubMed:22441691}. This is the function of NEURL4 (neuralized E3 ubiquitin protein ligase 4, Ensembl gene identifier ENSG00000215041).