Probable E2 ubiquitin-protein ligase that catalyzes the covalent attachment of ubiquitin to target proteins. May facilitate the monoubiquitination and degradation of MTOR and CCNE1 through interaction with FBXW7. . This is the function of UBE2QL1 (ubiquitin conjugating enzyme E2 QL1, Ensembl gene identifier ENSG00000215218).