The function of ENSG00000223573 (TINCR, TINCR ubiquitin domain containing) is as follows. Promotes epithelial differentiation by enhancing the sumoylation and activation of CDC42 (PubMed:36369429). Promotes keratinocyte proliferation (PubMed:32012357). This contributes to the maintenance of skin homeostasis by enhancing wound healing after skin injury (By similarity). Acts as a tumor suppressor in epithelial tumors (PubMed:36369429, PubMed:36899004). {ECO:0000250|UniProtKB:A0A1B0GRQ3, ECO:0000269|PubMed:32012357, ECO:0000269|PubMed:36369429, ECO:0000269|PubMed:36899004}.