The function of MIR155HG (MIR155 host gene, ENSG00000234883) is as follows. Negatively regulates MHC class II antigen presentation in dendritic cells by interacting with the molecular chaperone HSPA8 and impairing its role in lysosomal antigen transport (PubMed:32671205). Does not regulate the levels or activity of the MIR155HG microRNA from which miPEP155 is derived (PubMed:33810468). .