The function of BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex, Ensembl gene identifier ENSG00000254999) is as follows. Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). .