Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. (Microbial infection) Acts as a phagocytic receptor for bacteria, fungi and other pathogens. (Microbial infection) Acts as a receptor for Dengue virus envelope protein E. . (Microbial infection) Interacts with Hepatitis B virus envelope protein. . This is the function of MRC1 (mannose receptor C-type 1, Ensembl gene identifier ENSG00000260314).