The function of Ensembl gene identifier ENSG00000261308 (FIGNL2, fidgetin like 2) is as follows. Microtubule-severing enzyme that negatively regulates cell migration and wound healing (PubMed:25756798, PubMed:36523161). In migrating cells, targets dynamic microtubules (MTs) at the leading edge and severs them, thereby suppressing motility (PubMed:25756798, PubMed:36523161). Microtubule severing releases ARHGEF2 which activates RHOA, which in turn regulates focal ahesion turnover via focal adhesion kinase, as opposed to F-actin polymerization, to suppress cell motility (PubMed:36523161). Negative regulator of axon regeneration that suppresses axonal growth by selectively severing dynamic MTs in the distal axon shaft and growth cone (By similarity). Contributes to proper cell branching during endothelial and neuronal development (By similarity). {ECO:0000250|UniProtKB:E9QEA3, ECO:0000250|UniProtKB:J3QK54, ECO:0000269|PubMed:25756798, ECO:0000269|PubMed:36523161}.