The function of ENSG00000269964 (MEI4, meiotic double-stranded break formation protein 4) is as follows. Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with IHO1 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. .