Involved in the stimulation of renal sodium reabsorption mediated by the epithelial sodium channel (ENaC) (By similarity). Upregulates ENaC expression in renal collecting duct cells by promoting DOT1L export from the nucleus to the cytoplasm, thus limiting DOT1L- mediated H3K79 methylation and transcriptional repression at the SCNN1A promoter (PubMed:19864429, PubMed:22087315). {ECO:0000250|UniProtKB:B1AR09, ECO:0000269|PubMed:19864429, ECO:0000269|PubMed:22087315}. This is the function of Ensembl gene identifier ENSG00000275023 (MLLT6, MLLT6, PHD finger containing).