The function of PANO1 (proapoptotic nucleolar protein 1, Ensembl gene identifier ENSG00000288675) is as follows. Apoptosis-inducing protein that modulates the tumor suppressor function of CDKN2A/p14ARF. Enhances the stability of CDKN2A/p14ARF protein by protecting it from degradation. May act as a tumor suppressor (PubMed:22094112). .